Chiral and Achiral Profiling of a Pesticide Formulation Using the ACQUITY UPC2 System and the ACQUITY QDa Detector

IN T RO DU C T IO N Research associated with the development of new agricultural pesticide formulations centers around the design of products that provide highly effective and specific action towards the target organism with reduced application rates. It is estimated that 30% of the pesticides on the market today have optical isomers. However, the desired activities often result from one single enantiomer in the optical isomer mixtures. It is therefore important to assess the enantiomeric purity of the chiral active ingredients in the formulation. In addition, the detection, characterization, and quantitation of the other components in the formulation are necessary to support product registration.